HBeAb Rapid Test

Description

Intended Use

HBeAb Rapid Test (Whole blood/Serum/Plasma) is an in vitro diagnostic rapid immunochormatographic assay for the qualitative detection of Hepatitis B e Antibody (HBeAb) in human whole blood, serum and plasma specimens. The product may be used as an aid in the diagnosis of hepatitis B viral infection. A reactive result should be confirmed by other supplemental assay(s).

Introduction

Hepatitis B is a potentially life-threatening liver infection caused by the hepatitis B virus (HBV). It is a major global health problem. It can cause chronic infection and puts people at high risk of death from cirrhosis and liver cancer. About a third of the world population has been infected at one point in their lives, including 343 million who have chronic infections.1,2, 3 Many people have no symptoms during the initial infection1. Some develop a rapid onset of sickness with vomiting, yellowish skin, tiredness, dark urine and abdominal pain1. The virus is transmitted by exposure to infectious blood or body fluids1.

Hepatitis B e antibody is a viral protein secreted by HBV-infected cells. The presence of antibody against hepatitis B viral e antigen is used as an indicator for early HBs antigenemia before the peak of viral replication and early convalescence when HBeAg has declined below detectable levels. It is also useful to confirm a seroconversion. The seroconversion from HBeAg positive to anti-Hbe positive indicates a reduced level of infectious virus because virus replication has decreased.

HBeAb Rapid Test (Whole Blood/Serum/Plasma) is a rapid test to qualitatively detect the presence of HBeAb in whole blood, serum or plasma specimens. This test is very sensitive and only takes about 10-20 minutes. Test results are read visually without any instrument.