Rotavirus-Adenovirus-Norovirus-Astrovirus Combo Test
Infectious Disease TestsTesting KitsRotavirus-Adenovirus-Norovirus-Astrovirus Combo Test (Feces) is a rapid visual immunoassay for the qualitative presumptive detection of rotavirus, adenovirus, norovirus in human fecal specimens.
Description
Intended Use
Rotavirus-Adenovirus-Norovirus-Astrovirus Combo Test (Feces) is a rapid visual immunoassay for the qualitative presumptive detection of rotavirus, adenovirus, norovirus in human fecal specimens. Rotavirus-Adenovirus-Norovirus-Astrovirus Combo Test is intended to be used as an aid in the diagnosis of rotavirus, adenovirus, norovirus infection.
Introduction
Acute gastroenteritis is a common disorder in young children, and associated dehydration is a leading cause of admission to hospital in industrialized countries and a major source of mortality in developing countries. Symptoms may include diarrhea, vomiting, and abdominal pain. Fever, lack of energy, and dehydration may also occur. This typically lasts less than two weeks. Enteric viruses have been recognized as the most significant etiological agents of the disease, and currently rotavirus, adenovirus 40/41, norovirus, and astrovirus have been recognized as the most significant pathogens of childhood viral gastroenteritis.
Rotavirus is the most common cause of gastroenteritis in children. Viruses cause about 70% of episodes of infectious diarrhea in the pediatric age group. Adenoviruses, primarily Ad40 and Ad41, are a leading cause of diarrhea in many of these children, second only to the rotaviruses. Infections are most frequently seen in children less than two years of age, but have been found in patients of all ages. Further studies indicate that adenoviruses are associated with 4-15% of all hospitalized cases of viral gastroenteritis9. Norovirus is the leading cause of gastroenteritis among adults in America, causing greater than 90% of outbreaks10. These localized epidemics typically occur when groups of people spend time in close physical proximity to each other, such as on cruise ships, in hospitals, or in restaurants. Noroviruses commonly isolated in cases of acute gastroenteritis belong to two genogroups: GI and GII. People may remain infectious even after their diarrhea has ended10. Astroviruses are now recognized as a cause of gastroenteritis in children (<5 yr), whose immune systems are underdeveloped, and elderly adults, whose immune systems are generally somewhat compromised1. A study of intestinal disease in the UK, published in 1999, determined incidence as 3.8/1000 patient years in the community, the 4th most common known cause of viral gastroenteritis.
Gastroenteritis is typically diagnosed clinically, based on a person’s signs and symptoms. However, stool cultures should be performed in those with blood in the stool, those who might have been exposed to food poisoning, and those who have recently traveled to the developing world8. It may also be appropriate in children young than 5, old people, and those with poor immune function. Diagnostic testing may also be done for surveillance10. The RV-ADV-NOV-ASV Combo Rapid Test (Feces) is a simple, qualitative lateral flow immunoassay for the detection of rotavirus, adenovirus, norovirus and astrovirus infection.
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