• Main ingredient of ProGsterol is Deglusterol.

• Deglusterol is a synthetic peptide mixture made up of two peptides (Adiporin and Deobetide).

• Deglusterol breaks down into amino acids.

• These peptides consist of 5 and 9 amino acids respectively: alanine, arginine, asparagine, glycine, leucine, lysine, methionine, serine, and threonine. Each sachet contains 30 mg of Deglusterol.

Peptides are short chains of amino acids (the building blocks of proteins), typically made up of 2 to 50 amino acids linked together. They play crucial roles in the body, acting as signaling molecules, hormones, and building blocks for various biological functions. For e.g.

• Hormone Regulation:

• Signaling and Communication

• Immune Support:

• Muscle Growth and Repair:

• Metabolic Regulation

• Anti-Inflammatory and Antioxidant Effects:

In supplements like ProGsterol, peptides are designed to target specific pathways or functions. The peptides in ProGsterol helps improve insulin sensitivity and reduce inflammation, supporting blood sugar management and metabolic health.

Deglusterol is used for treating insulin resistance-related diseases, including:

• Type II diabetes

• Pre-diabetes

• Obesity

• Metabolic dysfunction-associated steatotic liver disease (MASLD)

• Non-alcoholic fatty liver disease (NAFLD)

• Polycystic ovary syndrome (PCOS)

It helps improve insulin sensitivity, reduce inflammation, enhance glucose uptake, and promote lipid metabolism.

• Activation of the AMPK Pathway: Deglusterol activates the AMPK pathway, which plays a crucial role in enhancing insulin sensitivity and promoting glucose uptake in cells.

• Down-Regulation of Inflammation: It decreases the levels of inflammatory cytokines such as TNF-α, IL-1β, and other molecules that

• Inhibition of Insulin Resistance Signals: Deglusterol reduces the phosphorylation of insulin resistance-related signaling molecules, which are typically elevated in the presence of inflammatory cytokines.

• Increase in Insulin Sensitivity Signals: It restores and increases the levels of insulin sensitivity molecules, including phospho-IRS (Tyr632), phospho-PI3K, phospho-AKT, and phospho-AMPK, which are essential for effective insulin signaling.

By addressing both inflammation and insulin signaling pathways, Deglusterol effectively reduces insulin resistance.

In ProGsterol, AMPK (AMP-activated protein kinase) plays an essential role in enhancing insulin sensitivity and supporting metabolic health. Here’s how AMPK contributes:

1. Improves Insulin Sensitivity: By activating the AMPK pathway, ProGsterol helps cells respond better to insulin, which means glucose can be taken up more efficiently from the bloodstream and used for energy. This can help lower blood sugar levels and improve overall glucose metabolism.

2. Promotes Energy Balance: The activation of AMPK encourages the body to burn stored fat and use it for energy. This supports weight management and reduces fat buildup, including around the liver and organs.

3. Reduces Inflammation: AMPK activation can help reduce inflammation in the body by inhibiting inflammatory pathways. Since inflammation is often linked to insulin resistance, this action helps improve metabolic function.

4. Enhances Metabolic Pathways: ProGsterol's effect on AMPK increases the expression of proteins involved in glucose uptake (like GLUT-4) and lipid metabolism, leading to better overall energy use and storage.

In summary, AMPK in ProGsterol helps to regulate energy use, reduce inflammation, and improve how the body handles insulin and blood sugar.

In ProGsterol, the down-regulation of inflammatory cytokines plays a crucial role in improving insulin sensitivity and supporting metabolic health. Here’s how it works:

1. Reducing Insulin Resistance: Inflammatory cytokines like TNF-α are known to interfere with insulin signaling, contributing to insulin resistance. By down-regulating these cytokines, ProGsterol helps improve how cells respond to insulin, enabling better glucose uptake and blood sugar control.

2. Lowering Chronic Inflammation: Chronic inflammation is linked to various metabolic disorders, including type 2 diabetes and fatty liver disease. ProGsterol’s ability to suppress the production and activity of inflammatory cytokines helps reduce inflammation throughout the body, supporting healthier metabolic function.

3. Supporting Weight Management: By reducing inflammation, ProGsterol helps regulate metabolic pathways that affect energy balance and fat storage. This can assist in weight management and prevent the buildup of excess fat, especially around vital organs.

4. Enhancing Overall Metabolic Health: By controlling inflammatory responses, ProGsterol helps create a more balanced metabolic environment. This not only supports better insulin action but also promotes improved lipid metabolism, aiding in cholesterol management and overall cardiovascular health.

In summary, the down-regulation of inflammatory cytokines in ProGsterol is vital for reducing inflammation, improving insulin response, and supporting healthy metabolism, making it beneficial for managing blood sugar levels and preventing metabolic issues.

It refers to the process of blocking or reducing the biochemical pathways and signals that lead to insulin resistance in the body. Insulin resistance occurs when cells do not respond properly to insulin, resulting in impaired glucose uptake and higher blood sugar levels. This can lead to conditions such as type 2 diabetes and metabolic syndrome.

ProGsterol plays a key role in inhibiting insulin resistance signals by:

• Reducing Inflammatory Molecules: It lowers the activity of inflammation-related signaling molecules like TNF-α, JNK, and NF-kB, which are known to interfere with insulin signaling.

• Supporting Insulin Pathways: By blocking these disruptive signals, ProGsterol helps maintain the normal function of insulin signaling pathways, enhancing the body’s ability to manage blood sugar levels.

• Activating Beneficial Pathways: ProGsterol promotes pathways that improve insulin sensitivity, such as PI3K/AKT and AMPK, which support glucose uptake and energy regulation.

In essence, inhibition of insulin resistance signals helps improve how the body responds to insulin, reducing the risk of high blood sugar levels and associated metabolic disorders.

It refers to the biochemical pathways and signals that promote a positive response to insulin, allowing cells in the body to effectively absorb glucose from the bloodstream. When cells are sensitive to insulin, they can take up glucose efficiently, which helps maintain normal blood sugar levels and supports overall metabolic health.

ProGsterol enhances insulin sensitivity signals by:

• Activating Beneficial Pathways: It supports pathways like PI3K/AKT and AMPK that promote insulin sensitivity.

• Increasing Protein Expression: It boosts levels of important proteins like GLUT-4, which helps transport glucose into cells.

• Reducing Inflammation: By lowering inflammatory cytokines that interfere with insulin signaling, ProGsterol improves how cells respond to insulin.

In summary, insulin sensitivity signals are vital for effective glucose uptake and metabolic health, ensuring that the body uses insulin efficiently to maintain normal blood sugar levels.

• It can reduce blood sugar levels (for pre-diabetics & type 2 diabetics)

• Reduce Insulin resistance which is the root cause of many health problems.

• It helps lose extra weight by avoiding sugar spikes in the body.

• Reduces Inflammation in the body.

• Improves Fatty liver disease (NAFLD)

• Enhances lipid metabolism, resulting in a decrease in triglycerides and cholesterol levels.

• Pre-diabetics and type II diabetics can take 1 stick per day.

• For weight loss, anyone can take 2 sticks per day. We recommend taking 1 stick before breakfast and 1 before dinner.

• No side-effects. We have completed preclinical studies and human clinical trials to evaluate safety, and its efficacy and safety have been confirmed. Peptides are a combination of amino acids. Under the action of endogenous enzymes, they break down into simple amino acids, which are nutrients for the body and are safe for the body as a whole.

• ProGsterol can be consumed by mixing a stick with a glass of water or any other drink.

• • Yes, it is safe to take ProGsterol with your regular medications. However, you must check your reading and discuss with your doctor if your readings are improving.

• Yes, ProGsterol can be beneficial for weight loss when combined with a healthy diet and moderate physical activity.

Yes, ProGsterol helps in reducing cholesterol and triglycerides levels as part of its broader support for metabolic health. While ProGsterol's primary focus is on improving insulin sensitivity and blood sugar control, its actions on AMPK activation, reduction of inflammation, and improved lipid metabolism can help in lowering cholesterol levels as part of a comprehensive approach to metabolic health.

• No tests have been conducted on children and pregnant women. Therefore, we cannot recommend ProGsterol for children and pregnant women.

• • Healthy eating and physical activity are always recommended for overall health. Therefore, while taking ProGsterol we do recommend eating healthy foods and some physical activity. However, if you crave sweets, we recommend taking ProGsterol before eating sweets.

• People with type 1 diabetes.

• People with cancer and kidney disease.